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Oprah Winfrey was set to announce Friday that her powerhouse daytime television show, the foundation of a multibillion-dollar media empire with legions of fans, will end its run in 2011 after 25 seasons on the air.

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Rome is known for its ancient monuments and classical paintings, but so far Italy's capital has been off the map of contemporary art fans. However with MAXXI, the new National Museum of 21st Century Arts, the city is trying to change that. We get a tour of the stunning structure, the brainchild of none other than celebrity architect, Zaha Hadid. Duration: 01:28.

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Mothers are just as enthusiastic as teen girls for the latest movie in saga.

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The Black Crowes' lend the song "Shine Along" to this week?s "Y3W." (11/21/09)

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Talk show giant announces she'll end show in 2011. Who could take her place?

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At this year's London Film Festival, an African documentary got people talking. The movie was about ordinary people taking on the government and winning.

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The media environment is quite different today than it was when she signed on 25 years ago, Jason DeRusha reports (2:21).

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The Tella-Jerusalem project brings new joys to a small school in Tanzania--one of the heartwarming stories from THIN THREADS, the inspiring collection describing magical, life-changing moments in people�s lives. Compiled by Stacey K. Battat.

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The new film shattered the record for a midnight screening. Sandra Mitchell reports.

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Holding back tears, Oprah Winfrey told her studio audience Friday that she would end her show in 2011 after a quarter-century on the air, saying prayer and careful thought led her to her decision. (Nov. 20)

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Oprah Winfrey tells her studio audience Friday that she'll stop hosting her powerhouse daytime talk show in 2011 after 25 seasons on the air. (Nov. 20)

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Oprah Winfrey annouced friday she'll be signing off of her syndicated talk show after it's 25th season ends in 2011.

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The actor talks about his latest role.

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Outside Harpo Studios in Chicago, audience members and fans of Oprah Winfrey describe how the talk show host broke the news that her program is ending. (Nov. 20)

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'Twilight Saga' fans, also known as Twihards, queued up at cinemas in Los Angeles triggering record ticket sales for 'New Moon''s opening weekend. (Nov. 20)

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A nude photograph of Carla Bruni-Sarkozy taken by Michel Comte during her modelling days goes under the hammer on Friday at a Paris auction house. A similar nude shot of the wife of the French president went for 91,000 dollars -- three times more than its estimated bidding price -- in a New York sale last year. Still images.

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Cutting to the heart of it with the British rapper and Mercury Prize winner.

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Bollywood actor Amitabh Bachchan plays a boy who has progeria in the film "Paa."

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Natalie Cole, Russell Simmons and Joe Silver offer their views on Oprah Winfrey's announcement that her talk show will end in 2011. (Nov. 20)

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Snowboarder Shaun White tells AP's weekly Video Game Video how his creative impulses influenced his second Wii game. (Nov. 20)

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Pattinson's power of persuasion; Kate's caustic criticism and 'The Simpsons' spice up Sundays

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Winfrey to announce end of 'The Oprah Winfrey Show'; Chris Brown has received 'extremely favourable' report from probation officials; Heidi Klum back in shape at Victoria's Secret show in New York. (Nov. 20)

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Robert Pattinson, Taylor Lautner and Kristen Stewart talk about their legion of 'twi-hard' fans and reveal their own obsessions. (Nov. 20)

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Chris Brown received an "extremely favorable" report from probation officials overseeing his felony assault case, a judge said Thursday. (Nov. 20)

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A new report says concession stand snacks may be making you fat.

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Oprah Winfrey's production company says she is ending her talk show in 2011. (Nov. 19)

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Fresh off of the release of the deluxe edition of their eponymous sophomore album, The Fray talk about what fans can expect from the new material and how to live in the shadow of their mega hit, 'How to Save a Life.' (Nov. 19)

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Actor tells of rough conditions on film set, bond with young co-star

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Comedian Dane Cook says he's grown up and so has his comedy. You can see that for yourself in his new standup DVD 'ISolated INcident.' The funnyman also moonlights as an actor and says entertaining people is his passion. (Nov. 19)

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Part 5: Jackson says Dr. Murray should not be allowed to practice medicine.

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Part 2: Janet tells Robin Roberts: "I felt that [Michael] was in denial."

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Part 1: Superstar tells Robin Roberts that Michael's death "felt like a dream."

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Hundreds of screaming fans turned up in London's Leicester Square to catch a glimpse of 'High School Musical' heartthrob Zac Efron at the world premiere of his latest movie 'Me and Orson Wells.' (Nov. 19)

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Elisabeth Leamy looks at the health content of oils used to make popcorn.

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"New Moon" heartthrob faces a female fan who loses her clothing for him.

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Nicole Richie hospitalized with pneumonia; Janet Jackson talks about Michael's drug problem; Taylor Swift to debut greeting card line in spring. (Nov. 19)